Build a HIV-Protease Target PROTAC
Open PROTAC Builder with an HIV protease target ligand preselected so you can continue into recruiter and linker selection.
Open HIV protease examplePROTAC Builder Examples
These examples are discovery-oriented workflow patterns rather than claims of validated degrader performance.
Use them to understand how PROTAC Builder fits into component selection, API automation, and downstream modeling handoff.
Example workflows
Build a CRBN-based PROTAC
Open PROTAC Builder with the CRBN recruiter preset for recruiter-side exploration.
Open CRBN in BuilderBuild a VHL-based PROTAC
Open PROTAC Builder with the VHL recruiter preset for recruiter-side exploration.
Open VHL in BuilderUse a custom warhead SMILES
Open PROTAC Builder with a starter custom SMILES value so you can test the custom input workflow.
Open custom SMILESMove from Warhead Hunter to PROTAC Builder
Use warhead-first discovery before returning to degrader assembly.
Explore Warhead Hunter ↗Move from E3 Ligandalyzer to PROTAC Builder
Inspect recruiter and scaffold context, then return with a session-aware handoff when available.
Explore E3 Ligandalyzer ↗Use V-LiSEMOD for a viral target warhead concept
Review viral protein-ligand structures and solvent-exposed moieties before returning to PROTAC Builder for assembly.
Explore V-LiSEMOD ↗Batch-generate PROTACs with the API
Prepare batch-oriented workflows from the API Builder and API docs.
Open API BuilderExport to downstream modeling workflows
Prepare componentized outputs for restrained ternary modeling and related evaluation.
View downstream toolsRun descriptor and prediction workflows
Use documented ADMET and DeepPK-adjacent outputs when supported.
Read API docs